Seth's Blog

A reader named Tim G commented:

Blood tests last year [2011] showed I had low Vitamin D levels so I was put on a 50,000 IU once/week regimen for 3 months using a prescription D2 (ergocalciferol). A recheck after 3 months showed my level had hardly changed. A search of PubMed showed conflicting views on using the D2 form. So for the next 3 months I used ProHealth D3 Extreme 50,000 IU (via Amazon.com) instead of another D2 scrip my doc had given me. I always took the D2 or D3 in the morning (just lucky happenstance.)

The second recheck, after the second 3 mo., showed my Vitamin D level was normal. I hadn’t put it all together until seeing this post, but when using the D3 I had the same effect [as what is described in this post] — when I got tired, I got *really* tired right at bedtime, and slept like a rock.

Even though it has been less than a month since stopping the weekly dose, I have noticed my sleep degrading somewhat, and lately not even being tired when I should.

I asked for details: (more…)

Jenny West, the Englishwoman who discovered independently the value of taking Vitamin D3 in the morning, wrote again:

Since reading some of the other D3 stories, I increased my D3 [morning] dosage to 5000 IU/day [from 3000 IU/day] two days ago.

1. I immediately slept even better – no longer being aware of mid-sleep turning-over.

2. I’ve had a large boost of energy and the clarity of thought that both Robin Barooah and Alexandra Carmichael mentioned.

3. A year-long injury – specifically a dislocated coccyx – has suddenly taken a step forward, and I found myself running for the  Tube last night – something I can’t remember when I last did it. Is this a direct effect of the D3, or an indirect one resulting from much better sleep?

This agrees with what both Alexandra and I experienced: a dose of 4000 IU worked much better than a dose of 2000 IU.

• Independent discovery of nose-clipping? Nasal soft strips reduce appetite, according to an infomercial.
• Does it matter how you take Vitamin D? A little bit of research.
• Hypercalcemia (too much calcium in the blood) after patient takes 5500 IU/day Vitamin D3 plus 2000 mg/day calcium.
• Fat Chef. A new TV show on the Food Network. Chefs try to lose weight.
• Kickstarter project: Restaurant guide to San Francisco on a map folded in a new way.
• The acne-diet connection. Dermatologists — the supposed experts — continue to say they aren’t connected.

Thanks to Anne Weiss, Phil Alexander and Dave Lull.

Alex Chernavsky, who has used the Shangri-La Diet successfully for two years, recently commented as follows (emphasis added):

For what it’s worth, I’ve taken Vitamin D at different times of the day, and I’ve never noticed any effect on my sleep. Of course, my sleep is already pretty good, in the sense that I fall asleep quickly and don’t usually wake up during the night. (My sleep is not good in the sense that I don’t get enough of it.)

By email, I learned that Alex is now taking Vitamin D3 — this particular product, which is vegan (“plant-source”) — at 5000 IU every other day. On weekdays, he takes it at about 8:00 am, on weekends, 9:30-10:00 am.

What might explain Alex’s failure to notice better sleep?

1. Not enough D3. I found that 2000 IU/day had no noticeable effect, whereas 4000 IU/day did produce noticeable benefit. Alex is getting 2500 IU/day — or less, if he takes it too late on the weekends.

2. His source of D3.

3. Individual differences large enough to matter. If you do sensitive psychology experiments, you will learn there are individual differences in everything.

4. Ceiling effect. Alex’s sleep is too good to notice improvement.

Those are the just the obvious possibilities.

I have heard many stories about Vitamin D3 and sleep, often in the comments section of this blog. From now on I am going to number them. (I retitled earlier posts.)

Elizabeth Funderburk emailed me:

I’ve always suffered, rather lightly I guess, from SAD in the winter.  In 2010 I started eating primal, which I thought would help – it helped in many ways but I still got gloomier all winter and didn’t even realize it til that first warm sunny spring day when I “woke up.” Your November post about D3 reminded me that I wanted to try it this winter, so I got a bottle and started taking it in the morning. I forgot a few times and took it in the midday or afternoon, and yes, I felt noticeably more spazzy and awake those evenings. Now, if I forget, I just skip it if I remember later than 10 am. I do think I sleep better. I take 4000-6000 IU daily.

I asked her for details.

Tell me about yourself.

I live in Reno, NV, USA, and I’m 34.  I do home renovations.

What brand?

Kirkland D3 2000 IU gelcaps. The first bottle I got was from Walgreen’s, so I guess it was Nature’s Bounty gelcaps. Both seem to work equally well. I have not tried capsules. I take the D3 while I’m waiting for my coffee, usually 6 or 7 am.

How has your sleep improved? (more…)