Stagnation in Psychiatry

A recent New York Times article lays it out:

Fully 1 in 5 Americans take at least one psychiatric medication. Yet when it comes to mental health, we are facing a crisis in drug innovation. . . . Even though 25 percent of Americans suffer from a diagnosable mental illness in any year, there are few signs of innovation from the major drug makers.

The author has no understanding of the stagnation, yet is opinionated:

The simple answer [to what is causing the stagnation] is that we don’t yet understand the fundamental cause of most psychiatric disorders [what does "fundamental cause" mean? -- Seth], in part because the brain is uniquely difficult to study; you can’t just biopsy the brain and analyze it. That is why scientists have had great trouble identifying new targets for psychiatric drugs.

The great increase in depression has an environmental cause. Meaning that depressed brains (aside from the effects of depression) are the same as non-depressed brains. Someone who knows that would not talk about biopsying the brain.

You come to a room with a door. If you don’t know how a door works, you are going to do a lot of damage getting inside. That is modern psychiatry. I described a new explanation for depression in this article (see Example 2).

Thanks to Alex Chernavsky.

6 Responses to “Stagnation in Psychiatry”

  1. dearieme Says:

    “when it comes to mental health, we are facing a crisis in drug innovation”: the first clause there is redundant.

  2. Alex Chernavsky Says:

    I think the great increase in depression probably has multiple causes, one of which is quite ironic. Antidepressant drugs probably cause depression (or, at least, exacerbate it). See, for example:

    “Now Antidepressant-Induced Chronic Depression Has a Name: Tardive Dysphoria”

  3. elduderino Says:

    We also have a lot of stagnation in other areas of medicine. The advances are minimally incremental and, because of industrial interests, the effects are overstated. Take statins for example. The sad truth is that we had little revolution since vaccination and antibiotics.

    Seth: I agree. Also the bad effects are understated. And antibiotics are questionable: the bad effects could easily outweigh the good effects.

  4. Steve Greenleaf Says:

    Seth,
    Have you read Leah Greenfeld’s Mind, Modernity, Madness? I haven’t yet, but I’ve read a bit of it plus her blogs, which provide the main thesis. It seems very similar to the lines along which you are thinking, although she comes at the issue as an anthropologist & political scientist (and perforce, as a historian). A compelling & fascinating topic.

  5. Alex Chernavsky Says:

    @Steve Greenleaf, the book you referenced certainly looks interesting, but wow! $34.05 for just the Kindle edition!

    http://www.amazon.com/Mind-Modernity-Madness-Culture-Experience/dp/0674072766

  6. john Says:

    Hi, Seth, I’d just like to recommend you this reading: http://www.theverge.com/2013/8/21/4595712/gut-feelings-the-future-of-psychiatry-may-be-inside-your-stomach

    Hope you find it useful. Cheers!